Effects of Platelet Rich Plasma Containing Alginate Gel on Dairy Cows with Sole Ulcers

  • TANABE Takafumi
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • TSUZUKI Nao
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • SEO Jongpil
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • ISHII Mitsuo
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • YAMADA Kazutaka
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • HANEDA Shingo
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
  • TABATA Yasuhiko
    京都大学再生医科学研究所生体組織工学研究部門
  • SASAKI Naoki
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine

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Other Title
  • 乳牛の蹄底潰瘍に対する多血小板血漿混合アルギン酸ゲルの蹄底再生効果
  • ニュウギュウ ノ テイテイ カイヨウ ニ タイスル タケッショウバン ケッショウ コンゴウ アルギンサン ゲル ノ テイテイ サイセイ コウカ

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Abstract

The clinical effect of alginate gel containing platelet rich plasma (PRP) on dairy cows with sole ulcers was examined. Whole blood was collected from the patients and PRP was prepared so that there were five times more platelets than whole blood. Among 11 hooves of 7 dairy cows with sole ulcers, 6 were treated with alginate gel containing PRP (PRP group) and the remaining 5 were treated with alginate gel alone (control group). The percentage reduction in the size of the hoof defect and changes in lesion score and pain score by pressure were recorded at 1, 2, and 3 weeks after treatment. The percentage reduction in size of the defect, lesion score,and pain score were significantly lower at each assessment point in the treated group than those of the control group. From these results, alginate gel containing PRP could be an effective treatment method for sole ulcers in dairy cows.

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