Economical Effect of Butorphanol or Morphine on Anesthetic Induction Dose of Aflaxalone for Endotracheal Intubation in Dogs

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  • 犬におけるブトルファノールまたはモルヒネの併用による気管挿管時のアルファキサロン投与量減少効果
  • イヌ ニ オケル ブトルファノール マタワ モルヒネ ノ ヘイヨウ ニ ヨル キカンソウカンジ ノ アルファキサロン トウヨリョウ ゲンショウ コウカ

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Abstract

<p>The dose of alfaxalone (ALFX) required for endotracheal intubation was examined in a study of 42 dogs undergoing sterilization surgery. The dogs were classified based on whether they received intravenous butorphanol (BTR) (0.4 mg/kg) or subcutaneous morphine (MOR) (0.5 mg/kg) 15 minutes before anesthetic induction (pre-B and pre-M groups, respectively), or after intubation (post-B and post-M groups, respectively). The findings indicated that the doses of ALFX required for endotracheal intubation were 1.59±0.26 mg/kg in the pre-B group and 2.45±0.36 mg/kg in the post-B group, revealing a 35.1% reduction, and 1.30±0.38 mg/kg in the pre-M group and 2.42±0.52 mg/kg in the post-M group, revealing a 46.2% reduction (P＜0.05). The dose of ALFX required for endotracheal intubation was found to have decreased when ALFX was administered in combination with BTR or MOR. </p>

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