<i>In vitro</i> evaluation of H<sub>2</sub>O<sub>2</sub> hydrothermal treatment of aged titanium surface to enhance biofunctional activity

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  • YONEYAMA Yuya
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Tokyo
  • MATSUNO Tomonori
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Tokyo
  • HASHIMOTO Yoshiya
    Department of Biomaterials, Osaka Dental University
  • SATOH Tazuko
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Tokyo

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  • In vitro evaluation of H2O2 hydrothermal treatment of aged titanium surface to enhance biofunctional activity

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Description

Surface modification of titanium has been extensively investigated in implant science and technology in an effort to improve its osteoconductivity. The rate of protein adsorption on titanium surfaces is known to vary depending on the chemistry, structure, morphology, and titanium-specific biological aging of the surface. It is thus desirable to modify smooth titanium surfaces of miniimplants used as orthodontic anchors immediately prior to use. In this study, we have developed a simple surface modification of titanium alloy that improves its biofunctional activity. The surface of a Ti-6Al-4V disk was modified by applying 3% H2O2 hydrothermal treatment using an autoclave. A nanostructured porous network TiO2 was observed on the treated surface. Treated surfaces exhibited higher hydrophilicity, protein adsorption, and cell proliferation than untreated surfaces. 3% H2O2 hydrothermal treatment is thought to provide biofunctional activity for aged titanium surface.

Journal

  • Dental Materials Journal

    Dental Materials Journal 32 (1), 115-121, 2013

    The Japanese Society for Dental Materials and Devices

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