Epidural Administration of Morphine for Postoperative Analgesia in Dogs.

  • MORIMOTO Keiko
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • OHTA Minoru
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • NISHIMURA Ryohei
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • MATSUNAGA Satoru
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • MOCHIZUKI Manabu
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • SASAKI Nobuo
    Laboratory of Veterinary Surgery Division of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo

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Other Title
  • モルヒネの硬膜外投与による犬の術後鎮痛効果
  • モルヒネ ノ コウマク ガイ トウヨ ニ ヨル イヌ ノ ジュツゴ チンツウ コウカ

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Abstract

To evaluate the analgesic effect of epidural morphine in dogs, a clinical trial was performed using 119 dogs that underwent various surgical operations at Veterinary Hospital of the University of Tokyo. The pain score, sedation score, heart rate and respiratory rate were recorded at 0. 5, 2, 4, 8, 12, 18, 24 hours after the surgery (extubation: time 0) . From 0.5 to 18 hours after the surgery, the dogs administerd with morphine showed statistically lower values in pain score compared with control group. Except for some dogs that had received the major operation in the upper abdomen or some orthopedic cases, epidural administration of morphine provided sufficient analgesic effects against postoperative pain. Even in high risk patients or geriatric dogs, there were no side effects caused by administration of morphine, such as hypopnea.

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