A Scleroderma-like Lesion in a Rabbit with Leydig Cell Tumors
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- KOJIMOTO Atsuko
- Aoba Animal Hospital Heart Animal Clinic
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- NAITOH Harumichi
- Heart Animal Clinic
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- OZAKI Saki
- Heart Animal Clinic
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- SUZUKI Shinichi
- Heart Animal Clinic
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- MURAKOSHI Naoko
- Heart Animal Clinic
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- YOKOTA Kazuya
- Heart Animal Clinic Miyata Animal Hospital
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- UCHIDA Kazuyuki
- Department of Veterinary Pathology, Faulty of Agriculture, Miyazaki University
Bibliographic Information
- Other Title
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- 強皮症様病変とライディッヒ細胞腫がみられたウサギの一例
- Scleroderma like Lesion in a Rabbit with Leydig Cell Tumors
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Abstract
A diffuse skin thickening lesion with partial nodular formation in the dorsal lumbar area was found in a 6-year-old male rabbit. Skin biopsy of the nodular lesion revealed a thin epidermis and abundant collagen production in the dermis and subcutis with atrophy of appendages. Findings were mostly consistent with human scleroderma. Three months after the initial examination, enlargement of the left testis was noted, and castration was performed. Histopathological examination demonstrated that both testes were Leydig cell tumors. The high serum testosterone level before castration decreased to within a normal range after castration with partial improvement of the skin lesions. These findings suggest that the Leydig cell tumors in this case caused secretion of excessive testosterone, possibly contributing to the formation of a scleroderma-like lesion.<br>
Journal
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- Japanese Journal of Veterinary Anesthesia & Surgery
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Japanese Journal of Veterinary Anesthesia & Surgery 37 (2), 39-42, 2006
Japanese Society of Veterinary Anesthesia & Surgery
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Keywords
Details 詳細情報について
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- CRID
- 1390282679697391232
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- NII Article ID
- 130004448768
- 10018466004
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- NII Book ID
- AN10158155
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- ISSN
- 13497669
- 09165908
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- NDL BIB ID
- 8624427
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed