PREOPERATIVE CHEMORADIOTHERAPY USING SUPERSELECTIVE INTRAARTERIAL INFUSION VIA SUPERFICIAL TEMPORAL ARTERY FOR STAGE III, IV ORAL CANCER
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- TOHNAI Iwai
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- HAYASHI Yasushi
- Department of Oral and Maxillofacial Surgery, Nagoya Daini Red Cross Hospital
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- SHIGETOMI Toshio
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- MITSUDO Kenji
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- FUKUI Takafumi
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- FUKUHARA Hirokazu
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- YAMAMOTO Noriyuki
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- NISHIKAWA Masaya
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
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- ISHIGAKI Takeo
- Department of Radiology, Nagoya University Graduate School of Medicine
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- FUWA Nobukazu
- Department of Radiation Oncology, Aichi Cancer Center
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- UEDA Minoru
- Department of Maxillofacial Surgery, Nagoya University Graduate School of Medicine
Bibliographic Information
- Other Title
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- Ｓｔａｇｅ ＩＩＩ，ＩＶ口腔癌に対する浅側頭動脈よりの超選択的動注法を用いた術前放射線化学療法
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Abstract
Thirty-eight patients with stage III, IV oral cancer were treated by preoperative chemoradiotherapy using superselective intraarterial infusion via the superficial temporal artery. Radiotherapy (total dose: 40Gy) and chemotherapy using CBDCA (total dose: 460mg/m2) were performed daily, followed by surgery. Catheter-insertion of 34 patients was done successfully. Four catheter insertions were not done successfully because of the anomaly of the artery such as common trunk of the lingual artery and the facial artery. The clinical effects were CR in 9 patients (26.5%) and PR in 25 (73.5%), and histopathological effects after surgery were grade III, IV in 10 (29.4%), grade IIb in 23 (67.6%), and grade IIa in 2 (5.8%). The 5-year cumulative survival rate was 67.8%. This superselective intra arterial infusion method could be the technique of choice for the treatment of oral cancer.
Journal
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- Japanese jornal of Head and Neck Cancer
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Japanese jornal of Head and Neck Cancer 28 (1), 253-258, 2002
Japan Society for Head and Neck Cancer
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Keywords
Details 詳細情報について
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- CRID
- 1390282679704635392
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- NII Article ID
- 130004166838
- 10012171420
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- NII Book ID
- AN00165234
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- ISSN
- 18839878
- 09114335
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed