A critical consideration for "the standardization of evaluation of analgesics efficiency in toothache". Clinical study of acetoaminophen.

DOI
  • SAITO TSUYOSHI
    Department of Endodontics, Nihon University, School of Dentistry
  • ASAI YASUHIRO
    Department of Endodontics, Tokyo Dental College
  • IKEDA KATSUMI
    Department of Periodontology, School of Dentistry, Meikai University
  • OHNO TOSHIKO
    Department of Pharmacy, Nihon University Dental Hospital
  • KOHNO ATSUSHI
    Department of Operative Dentistry, Tsurumi University, School of Dental Medicine
  • SAKAIZUMI KAZUO
    Oral Surgery, School of Medicine, Tokai University
  • HASEGAWA KOHJI
    Department of Periodontics, School of Dentistry, Showa University
  • HIGAKI MORIO
    Department of Pedodontics, Kanagawa Dental College
  • FURUYA HIDEKI
    Department of Anesthesiology, The Nippon Dental University, School of Dentistry at Tokyo
  • MATSUMOTO AKIRA
    Department of Dental Pharmacology, School of Dentistry, Hokkaido University
  • WATANUKI KEN
    Department of Endodontics, Ohu University School of Dentistry
  • KOMORI NORIO
    Department of Endodontics, Nihon University, School of Dentistry
  • ARIIZUMI MINORU
    Department of Endodontics, Nihon University, School of Dentistry

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Other Title
  • “歯痛に対する鎮痛剤の効果判定基準”の検討　とくにアセトアミノフェンを用いた治験成績
  • —Clinical study of acetoaminophen—
  • とくにアセトアミノフェンを用いた治験成績

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The purpose of this study is to criticize clinically“the standardization of evaluation of analgesics efficiency in toothache”which was executed by Japanese Society of Oral Therapeutics and Pharmacology.<BR>117 patients with toothache and related pain which needed analgesic drug were carried out in this study.<BR>2 Tablets of CALONAL 0 Tab.® (Showa Yakuhin kako Corp. 200mg acetoaminophen/1 tablet) were each administered without symptomatic intra-oral treatment.<BR>The following results were obtained from this study.<BR>1) Acetoaminophen is effective and safe for relieving toothache and related pain. 83% of experimental persons were obtained effective analgesics result.<BR>2) Side effect repoted in 3 of 117 cases (0.3%) : such as stomachache, drawsiness and dizziness. However, latter two cases were considered that there were no relationship with the administrating of CALONAL O Tab.<BR>3) “The standardization of evaluation of analgesics efficiency in toothache”was useful generally to evaluate the analgesic efficiency.

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