Cryptococcus neoformans Detected from a Ground-glass Opacity

Ogata Hiroaki, Harada Eiji, Imada Yusuke, Mikumo Hironori, Hamada Naoki, Fukuyama Satoru, Nakanishi Yoichi

doi:10.18907/jjsre.39.1_71

Bibliographic Information

Other Title

スリガラス影よりCryptococcus neoformansが検出された1例

Description

Background. Nodules, cavitations and consolidations are common radiological findings of pulmonary cryptococcosis, but ground-glass opacities (GGOs) are not. To our knowledge, Cryptococcus sp. has never been detected from GGOs in the literature. Case. A 63-year-old man, who underwent renal transplant 16 months previously, was admitted to our hospital because of nodules in the right lower lung lobe on chest computed tomography (CT). One month later, chest CT showed not only nodules but also multiple GGOs. Bronchoscopy was performed, and the bronchoalveolar lavage fluid from the right B⁵, the segment where there was only a GGO and were not any nodular lesions, revealed Cryptococcus neoformans, leading to a diagnosis of pulmonary cryptococcosis. He was treated with fosfluconazole and fluconazole, and the GGOs improved within a few weeks. Conclusion. This is the first report of pulmonary cryptococcosis in which Cryptococcus sp. was detected from a GGO. We should suspect this disease when we see a GGO on CT.

Journal

The Journal of the Japan Society for Respiratory Endoscopy

The Journal of the Japan Society for Respiratory Endoscopy 39 (1), 71-75, 2017

The Japan Society for Respiratory Endoscopy

Keywords

Details 詳細情報について

CRID: 1390282679731506944

NII Article ID: 130005345100

DOI: 10.18907/jjsre.39.1_71

ISSN: 21860149; 02872137

Text Lang: ja

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JaLC
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<i>Cryptococcus neoformans</i> Detected from a Ground-glass Opacity