Theory and Practice of Hemodilutional Autologous Transfusion

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  • HIROTA Kazuyoshi
    Department of Anesthesiology, Hirosaki University Graduate School of Medicine

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  • 希釈式自己血輸血の理論と実際

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<p>The amount of viruses in donated blood is too small to be detectable by infection examination（window period）just after a blood donor is infected with hepatitis B or C or HIV. In these cases, blood recipients may be at risk for these virus infections. In addition, recipients may also have donated blood-caused adverse reactions such as hemolytic transfusion reactions, anaphylaxis, TRALI and GVHD. For these reasons, we promote hemodilutional autologous transfusion（HAT）to avoid allogeneic transfusion. Based on our data analysis in patients undergoing non-cardiac surgery, the rate of HAT-caused hypotention with requirement of vasopressor was around 6%, and the rate of allogeneic transfusion avoidance by HAT was 94% and 40% when blood loss was less than and more than 2000 g, respectively. Therefore, HAT may be a useful technique in anesthesia management. However, HAT may not be suitable for aged patients and patients with coronary stenosis.</p>

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