アトロピン前投薬の効果の検討

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タイトル別名
  • Atropine before general anesthesia effects on airway secretion and heart rate.

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We investigated the effects of 0.25mg and 0.5mg i.m. atropine premedication on airway secretion and bradycardia during general anesthesia in 252 intubated patients. We also evaluated the effects of surgical positions or procedures on airway secretion.<br>Both 0.25mg and 0.5mg atropine premedication reduced the cases requiring airway suction significantly in comparison with the non-atropine group (P<0.05).<br>No significant differences were observed in bradycardia among three groups.<br>Although the number of cases requiring the airway suction decreased significantly with atropine premeditation, we suggest that routine use of atropine as premedication appears to be unnecessary because of negligible difference.<br>In respect of the surgical positions and surgical procedures, prone, knee-chest, and lateral positions required oropharyngeal suction in 36per cent and the surgical procedures, which stimulate the airway, required tracheobronchial suction in 38per cent. Premedication with atropine tended to reduce the requirement of the airway suction.<br>In conclusion, we consider that atropine as premedication for the surgical position increasing saliva or the surgical procedures stimulating the airway facillitate smooth conduct of anesthesia on airway secretion.

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