Monitored Anesthesia Care with Dexmedetomidine in an Infant with Partial Trisomy 16

DOI Web Site 8 References Open Access
  • OBINATA Hirofumi
    Department of Anesthesiology, Japan Self Defense Force Central Hospital
  • NISHIBE Shinichi
    Department of Anesthesiology, Saitama Medical University International Medical Center
  • NIIHARA Akiko
    Department of Anesthesiology, Maternal and Child Health Center, Aiiku Hospital

Bibliographic Information

Other Title
  • 部分型16トリソミーと診断された乳児に対するデクスメデトミジンの使用経験

Search this article

Description

<p>Partial trisomy 16, a rare chromosomal abnormality, is associated with various manifestations, such as growth and developmental retardation, central nervous system malformations, and craniofacial dysmorphism. To our knowledge, there have been no reported cases of anesthetic management in a patient with partial trisomy 16.</p><p>A 98-day-old girl（height, 51 cm；weight, 4.0 kg）with partial trisomy 16 underwent laryngofiberscopic examination and magnetic resonance imaging under monitored anesthesia care. Sedation was initiated with a bolus dose of midazolam（0.5 mg）. Dexmedetomidine was subsequently administered as a bolus of 0.8 μg/kg over 20 min followed by 0.8 μg/kg/h infusion. Ketamine（5 mg）was immediately added before inserting the laryngofiberscope. The examination was performed with spontaneous breathing via the natural airway. No episodes of adverse respiratory events or hemodynamic instability occurred. Dexmedetomidine is useful for sedation in patients with partial trisomy 16.</p>

Journal

References(8)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top