A case of low tone sensory nerve hearing loss with positive inner ear autoantibodies

DOI 24 References
  • Tomiyama Shunichi
    Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital
  • Saitou Akihiko
    Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital
  • Nonaka Manabu
    Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital

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Other Title
  • 低音障害型感音難聴―内耳自己抗体陽性一症例の治療経過―
  • 内耳自己抗体陽性一症例の治療経過

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Description

A case of acute low tone sensory nerve hearing loss with positive 68kDa inner ear autoantibody was reported. Prednisone 60mg administration and tapering was effective shortly. Fourth relapse of hearing loss occurred shortly after hearing recovery during steroid tapering.<BR>Then, combined therapy of cyclophosphamide and prednisone was initiated Hearing loss was completely recovered and normal hearing has been maintained for over 18 months. Consequently, it was suggested that autoimmune pathogenesis played an important role in this lowtone sensory nerve hearing loss.

Journal

  • Otology Japan

    Otology Japan 17 (1), 26-32, 2007

    Japan Otological Society

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