QRS morphology in the 87-lead body surface electrocardiograms predicts positive response to cardiac resynchronization therapy in patients with chronic heart failure

DOI 16 References
  • Yokokawa Miki
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Shimizu Wataru
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Noda Takashi
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Okamura Hideo
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Satomi Kazuhiro
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Suyama Kazuhiro
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Kurita Takashi
    Division of Cardiology, Department of Internal Medicine, Kinki University School of Medicine
  • Aihara Naohiko
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Kanzaki Hideaki
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center
  • Niwaya Kazuo
    Division of Cardiology, Department of Cardiovascular Surgery , National Cardiovascular Center
  • Kobayashi Junjiro
    Division of Cardiology, Department of Cardiovascular Surgery , National Cardiovascular Center
  • Kamakura Shiro
    Division of Cardiology, Department of Internal Medicine National Cardiovascular Center

Bibliographic Information

Other Title
  • ８７点体表面心電図におけるＱＲＳ波形による心臓再同期療法の有効性の予測

Search this article

Abstract

The QRS morphology in electrocardiograms (ECGs) shows the local activation pattern of the ventricular myocardium. The 87-lead body surface ECGs were recorded before and after (at 1 day, 1 month, and 3 months) cardiac resynchronization therapy (CRT) in 35 dilated cardiomyopathy patients with chronic heart failure (28 males, 58 ± 16 years, left ventricular ejection fraction 20 ± 8%). QRS morphology was evaluated in the two regions : 1) outflow tract (OT), reflecting the latest activation site in normal ventricle, 2) left ventricular (LV) postero-lateral wall (PL), reflecting LV epicardial pacing site. The OT-region was defined as D-F/5-6 (upper anterior chest leads), and the PL region was defined as J-L/3-4 (lower left back leads) among 87 leads, respectively. Among the 6 leads in each region, we compared the number of leads with dominant R-wave pattern (R-leads) and QS-wave pattern (QS-leads) between 21 responders and 14 non-responders. Before CRT, the number of R-leads and QS-leads were not different between responders and non-responders. After CRT, the number of R-leads in the OT region (R-OT) increased in responders, but did not change in non-responders. Furthermore, the number of QS-leads in the PL region (QS-PL) significantly increased in responders, but did not change in non-responders. The number of both R-OT and QS-PL after CRT did not change throughout the follow-up periods. The increase of R-wave pattern in the upper anterior chest leads and QS-wave pattern in the lower left back leads after CRT may predict responders to CRT.

Journal

References(16)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top