Progress Toward Understanding the Etiology of Otosclerosis and Implications for Future Management

DOI 参考文献54件
  • McKenna Michael J
    Department of Otology and Laryngology, Harvard Medical School Department of Otolaryngology, Massachusetts Eye and Ear Infirmary

書誌事項

公開日
2009
DOI
  • 10.11289/otoljpn.19.113
公開者
一般社団法人　日本耳科学会

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説明

Otosclerosis is a disease of the otic capsule that is among the most common causes of acquired hearing loss. During the last 15 years, our laboratory has focused on elucidating the molecular pathology of otosclerosis with the long-term goal of developing better forms of therapy. These studies have brought us to the point where we are ready to consider and develop new and innovative treatment strategies. We have identified a promising pharmacological treatment, have begun to develop and test a drug formulation for use in humans, and have developed an animal model with which to test this therapy.

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