Influence of Pre-treated Moisturizer on the Application of Lidocaine Tape for Patients Undergoing Dialysis

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  • 透析患者へのリドカインテープ貼付における保湿剤前処置の影響

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The study was performed to evaluate the effects of pre-treated heparinoid lotion on the adhesion (peeling force), amount of stripped striatum corneum and drug release rate from of lidocaine tape in patients undergoing dialysis. The subjects consisted of 10 males and 6 females (mean age: 65.8 ± 13.6 years). The application of heparinoid lotion significantly elevated the water content of the stratum corneum. The application of lidocaine tape in hydrated skin induced by heparinoid lotion significantly reduced the amount of stripped striatum corneum without influencing peeling force. The release rate from the patch showed a tendency to increase in hydrated skin induced by heparinoid lotion. These results suggest that the usability of lidocaine tape is improved by pre-treatment of heparinoid lotion.

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