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Risk of Mixing of Glass Pieces in Commercial Injections Predicted by Sedimentation Time Using Stokes Equations
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- Nakashima Kazuhiro
- Department of Pharmacy, Kyushu University Hospital
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- Okayama Miki
- Department of Pharmacy, Kyushu University Hospital
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- Matsumoto Nozomi
- Department of Pharmacy, Kyushu University Hospital
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- Sueyasu Masanori
- Department of Pharmacy, Kyushu University Hospital
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- Egashira Nobuaki
- Department of Pharmacy, Kyushu University Hospital
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- Oishi Ryozo
- Department of Pharmacy, Kyushu University Hospital
Bibliographic Information
- Other Title
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- ストークス式による予測沈降時間から考慮される市販注射薬のガラス片混入の危険性
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Description
There is little information on sedimentation time of glass pieces in glass ampoules. In this study, we predicted the sedimentation time of glass pieces in commercial injections using Stokes equations. First, we measured the viscosity and density of 21 types of commercial injection. The viscosity of injections changed largely with temperature, and the higher viscosity showed a longer predicted sedimentation time. Moreover, considering factors such as storage temperature and the height from bottom to surface of injections, the predicted sedimentation times of glass pieces was long, that is 3.9-19.0 min/ampoule at 20°C. These results suggest the risk of mixing glass pieces in parts of commercial injections.
Journal
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- Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
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Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) 39 (10), 581-586, 2013
Japanese Society of Pharmaceutical Health Care and Sciences
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Details 詳細情報について
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- CRID
- 1390282679752516096
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- NII Article ID
- 130004696145
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- ISSN
- 18821499
- 1346342X
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed