書誌事項
- タイトル別名
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- Characterization of collagens produced by rat hepatocyte in primary culture
- シロネズミ カン ジッシツ サイボウ ノ ショダイ バイヨウ ニ オケル コラ
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Hepatocytes were obtained from rat liver and maintained in primary culture for periods up to 14 days. Collagen synthesis was maximal after 3-5 days and declinied thereafter. Collagen types were identified with DEAE-cellulose, Agarose A15 m and CM-cellulose coloum chromatography. Type I procollagen and pepsin treated type I collagen were identified as a 450, 000 dalton molecule and a 95, 000 daoton molecule, respectively.<BR>Type III procollagen was suggested with DEAE-cellulose chromatography, but pepsin treated type III ollagen was not identified. These data suggest that rat hepatocytes in primary culture are capable of interstitial type I collagen and, presumably, type III collagen production.
収録刊行物
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- 肝臓
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肝臓 24 (4), 381-388, 1983
一般社団法人 日本肝臓学会
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詳細情報 詳細情報について
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- CRID
- 1390282679765710848
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- NII論文ID
- 130000871820
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL書誌ID
- 2628150
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可