肝動脈遮断後の肝酸素需給動態と肝静脈酸素飽和度との関係に関する実験的検討

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  • Experimental studies on the relationship between hepatic oxygen metabolism and hepatic venous hemoglobin oxygen saturation after hepatic artery ligation.

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We studied on the relationship between hepatic oxygen metabolism (hepatic oxygen delivery (HOD), hepatic oxygen consumption (HOC), and hepatic oxygen extractional ratio (HOER) and hepatic venous oxygen saturation (HVSat)) after hepatic artery ligation using mongrel dogs. After all hepatic arterial supply was ligated, HOD, HOC, HOER and HVSat changed to 53%, 85%, 169%, 76% of their initial values respectively. We found the correlation between HOD and HVSat (r=0.8956, p<0.002, Y=23.2 LN(X)+7.75), and between HOER and HVSat (r=-0.8853, p<0.002, Y=-0.92X+86.61). Value of HVSat in hepatic artery ligation group was significantly lower than 60% which concidered the lowest point of normal liver. Therefore we concluded that it would be useful to measure hepatic venous oxygen saturation continuously for monitoring hepatic artery obstruction.

収録刊行物

  • 肝臓

    肝臓 34 (1), 18-22, 1993

    一般社団法人　日本肝臓学会

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