Study on clinical and pathological findings of patients with minute hepatocellular carcinoma

  • KINAMI Yoshio
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • SHINMURA Koji
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • IZUMI Riyohe
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • TAKADA Michiaki
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • SUGAHARA Shojiro
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • SAKUMA Kan
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • SAKATA Noriaki
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • KURACHI Madoka
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • MIYAZAKI Itsuo
    The Second Department of Surgery, School of Medicine, Kanazawa University

Bibliographic Information

Other Title
  • 細小肝細胞がん例における臨床病理学的所見の検討
  • サイショウ カン サイボウ ガン レイ ニ オケル リンショウ ビョウリガクテ

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Abstract

To clarify the clinical significance of minute hepatocellular carcinoma, data on 12 patients with tumor less than 5cm in size seen in our clinic during the past 20 years were evaluated. All of these patients were male, and average age was 61 years old. Of these patients, 6 revealed positive HBs antigen or antibody in serum and 10 positive alpha-fetoprotein. Most of them exhibited a decreased functional reserve in the liver. Ten patients (38%) underwent hepatic resection, and 2 had conservative treatment. Operative mortality rate was 27%. Survival rates of these patients, excluding operative death, were 67% at one year, 33% at 3 years respectively. After treatment, 2 patients (40%) died of the recurrence of tumor, and 3 died of liver cirrhosis. Of overall patients, 64% had a capsule around tumor, and 92% associated with liver cirrhosis.<BR>From these findings, it is suggested that some of patients with minute hepatocellular carcinoma reveal a clinical feature of advanced tumor, and that the survival time of patients is fairly influenced by the prognosis of accompanied liver cirrhosis.

Journal

  • Kanzo

    Kanzo 23 (12), 1397-1402, 1982

    The Japan Society of Hepatology

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