Estimation of Causal Effects of Pregnant Women's Sensitivity to Cold (<i>hiesho</i>) on Uterine Inertia and Prolonged Labor: Adjustment of Confounding Factors by Propensity Scores

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  • 妊婦の冷え症と微弱陣痛・遷延分娩との因果効果の推定
  • 妊婦の冷え症と微弱陣痛・遷延分娩との因果効果の推定 : 頃向スコアによる交絡因子の調整
  • ニンプ ノ ヒエ ショウ ト ビジャク ジンツウ ・ センエン ブンベン ト ノ インガ コウカ ノ スイテイ : コロコウ スコア ニ ヨル コウラクインシ ノ チョウセイ
  • Estimation of Causal Effects of Pregnant Women's Sensitivity to Cold (hiesho) on Uterine Inertia and Prolonged Labor: Adjustment of Confounding Factors by Propensity Scores
  • —傾向スコアによる交絡因子の調整—

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Purpose: The purpose of this study is to analyze the difference in incidence of uterine inertia and prolonged labor between pregnant women with hiesho and those without hiesho and to estimate the causal effects.<br>Method: The study design was a retrospective cohort study. The analysis was conducted on 2,540 women in hospital after delivery, over the approximately twelve months between October 19, 2009 and October 8, 2010 (response rate: 60.8%). The research methods employed were a self-administered questionnaire and data extraction from medical records. In this analysis, confounding factors were adjusted by carrying out analysis of covariance and stratified analysis using propensity scores.<br>Results: Of study respondents, 41.9 percent had hiesho. The regression coefficient of hiesho was 0.69, p<0.001 and the odds ratio was 2.00 for uterine inertia (analysis of covariance). The regression coefficient of hiesho was 0.83, p<0.001 and the odds ratio was 2.38 for prolonged labor (analysis of covariance).<br>Conclusion: The incidence of uterine inertia was twice as high among pregnant women with hiesho than those without hiesho, and the incidence of prolonged labor was 2.3 times higher. It was inferred that hiesho may have causal effects on uterine inertia and prolonged labor.

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