Effect of alcohol consumption on the prevalence of fatty liver disease

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  • Doi Tadashi
    Department of Gastroenterology, Oji General Hospital
  • Tanaka Shingo
    Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
  • Sato Yasuhiro
    Department of Gastroenterology, Oji General Hospital
  • Ohta Hidetoshi
    Department of Gastroenterology, Oji General Hospital
  • Minami Shinya
    Department of Gastroenterology, Oji General Hospital
  • Fujimi Akihito
    Department of Hematology, Oji General Hospital
  • Kanisawa Yuji
    Department of Hematology, Oji General Hospital
  • Tamura Fumihito
    Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
  • Hirakawa Masahiro
    Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
  • Ono Kaoru
    Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine

Bibliographic Information

Other Title
  • 脂肪性肝疾患の頻度に及ぼすアルコール摂取の影響
  • シボウセイ カン シッカン ノ ヒンド ニ オヨボス アルコール セッシュ ノ エイキョウ

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Description

The effect of light to moderate alcohol consumption on the prevalence of obesity related fatty liver disease (FLD) is controversial. We analyzed 3185 individuals (male/female: 2243/939) who visited Oji General Hospital Health Checkup Center from January 2008 to December 2008. Multiple logistic regression was used to determine the association between alcohol consumption and FLD. Visceral fat obesity, impaired fasting glucose, and dyslipidemia were associated with increased Odds ratios for the fatty liver. On the other hand, in men, minimal (<20 g) to moderate alcohol consumption (=20 g and <40 g/day) was associated with decreased Odds ratio for fatty liver (FL). In women, however, alcohol consumption was not found to be associated with a decreased Odds ratio for FL. These results suggest that there is a sex difference in the effect of alcohol consumption on the prevalence of FLD and light to moderate alcohol consumption may have preventive effect on the developing obesity related FLD in men.<br>

Journal

  • Kanzo

    Kanzo 51 (9), 501-507, 2010

    The Japan Society of Hepatology

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