Time intensity curves of Sonazoid in portal vein in the patients with chronic liver disease and in healthy volunteers

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  • Ｓｏｎａｚｏｉｄ造影超音波検査における門脈内Ｓｏｎａｚｏｉｄ停滞時間に関する検討

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Abstract

Sonazoid, an ultrasonography contrast agent which consists of perflubutane microbubbles with shells, is stable in blood vessels and remains for a long time. We investigated time intensity curves of Sonazoid in portal vein in the patients with chronic liver disease and healthy volunteers. Among 25 patients with chronic liver disease, Sonazoid remained at the rates of 54.8±15.2%, 32.5±13.3%, 25.2±12.2%, 8.8±7.1% in the portal vein, 10, 20, 30, and 60 minutes after injection, respectively. In healthy volunteers, Sonazoid remained at the rates of 60.1±12.9%, 41.4±11.4%, 32.0±10.3%, 7.8±4.5% in the portal vein, 10, 20, 30, and 60 minutes after injection, respectively. It is recommended that Kupffer images of Sonazoid-enhanced contrast ultrasonography is evaluated 60 minutes after injection of Sonazoid to avoid an influence of sonazoid remaining in the vessels.<br>

Journal

  • Kanzo

    Kanzo 50 (10), 593-594, 2009

    The Japan Society of Hepatology

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