Case of acute hepatitis C contracted by contact with blood while administering first aid to a spouse with type C cirrhosis

DOI Web Site Web Site 19 References
  • Asai Yasutsugu
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Wakui Noritaka
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital Division of Gastroenterology and Hepatology, Toho University Omori Medical Center
  • Nishinakagawa Shuta
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Koyama Yohei
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Dan Nobuhiro
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital Division of Gastroenterology and Hepatology, Toho University Omori Medical Center
  • Takeda Yuki
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Ueki Nobuo
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Otsuka Takafumi
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital Division of Gastroenterology and Hepatology, Toho University Omori Medical Center
  • Oba Nobuyuki
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Kojima Tatsuya
    Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital
  • Sumino Yasukiyo
    Division of Gastroenterology and Hepatology, Toho University Omori Medical Center
  • Sugiyama Shinya
    The Research Center for Hepatitis and Immunoloy, National Center for Global Health and Medicine
  • Mizokami Masashi
    The Research Center for Hepatitis and Immunoloy, National Center for Global Health and Medicine

Bibliographic Information

Other Title
  • C型肝硬変の夫の創傷手当が感染契機と思われるC型急性肝炎の1例
  • 症例報告 C型肝硬変の夫の創傷手当が感染契機と思われるC型急性肝炎の1例
  • ショウレイ ホウコク Cガタ カンコウヘン ノ オット ノ ソウショウ テアテ ガ カンセン ケイキ ト オモワレル Cガタ キュウセイ カンエン ノ 1レイ

Search this article

Abstract

A 63-year-old woman visited our hospital complaining of general malaise and poor appetite and was admitted for liver dysfunction. She was subsequently diagnosed with acute hepatitis C based on positive test results for hepatitis C virus (HCV) antibody and HCV RNA, but not for other viral markers. Because of persisting liver dysfunction despite fluid administration and complete rest, she was started on 180 μg/week of pegylated interferon-α2a on hospital day 66. Transaminase levels improved and she was discharged on hospital day 88. Negative of HCV-RNA was obtained on hospital day 93. A careful medical history was taken to determine the cause of HCV infection and revealed that her husband with type C cirrhosis was injured in a fight approximately 3 months before the onset of her symptoms and that she had come into direct contact with his blood when administering first aid. Phylogenetic analysis of HCV strains isolated from the patient and her husband's sera samples showed 98.1% homology between their strains, indicating they had the same HCV strain. This case highlights the importance of providing appropriate explanation on preventing viral hepatitis infection to the family members of HCV-positive patients.

Journal

  • Kanzo

    Kanzo 56 (4), 144-149, 2015

    The Japan Society of Hepatology

References(19)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top