Infection route of hepatitis C patients treated with direct-acting antivirals -To evaluate the risk of reinfection-

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  • Yukawa Yoshimi
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Tamori Akihiro
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Teranishi Yuga
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Motoyama Hiroyuki
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Kozuka Ritsuzo
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Kawamura Etsushi
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Hagihara Atsushi
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Uchida-Kobayashi Sawako
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Morikawa Hiroyasu
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Enomoto Masaru
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Murakami Yoshiki
    Department of Hepatology, Graduate School of Medicine, Osaka City University
  • Fukushima Wakaba
    Department of Public Health, Graduate School of Medicine, Osaka City University
  • Kawada Norifumi
    Department of Hepatology, Graduate School of Medicine, Osaka City University

Bibliographic Information

Other Title
  • Direct-acting antivirals治療例におけるC型肝炎ウイルス感染経路の検討―再感染リスクを踏まえて―
  • Direct-acting antivirals チリョウレイ ニ オケル Cガタカンエンウイルス カンセン ケイロ ノ ケントウ : サイカンセン リスク オ フマエテ

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Abstract

<p>We analyzed 616 chronic hepatitis C patients who were treated with DAAs from Sep 2014 to Aug 2016 and eight acute hepatitis C patients after May 2007 in our hospital. 372 patients (60.4%) identified their infection routes via a blood transfusion, surgery, intravenous drug use (IDU), family history, and tattooing in 189, 279, 30, 18, and 24, respectively. There were no patients who were reinfected with HCV during the observation period of 34 months. Infection via IDU and tattooing still have a possibility for reinfection after SVR. These were predominant routes in young, male, and genotype 2 patients. In addition, patients who were lost to follow-up treatment showed the same backgrounds. Our data indicated that they may be candidates in a high risk group of HCV reinfection. We should observe and educate them more intensely.</p>

Journal

  • Kanzo

    Kanzo 58 (8), 435-440, 2017

    The Japan Society of Hepatology

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