A case of liver metastasis arising from gastric GIST 12 years after resection of primary GIST

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  • 術後12年目に切除しえた胃GIST肝転移の1例
  • 症例報告 術後12年目に切除しえた胃GIST肝転移の1例
  • ショウレイ ホウコク ジュツゴ 12ネンメ ニ セツジョ シエタ イ GIST カン テンイ ノ 1レイ

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Abstract

Liver is the most common site for metastasis of gastrointestinal stromal tumors (GIST). Liver metastasis often occurs within 2 years of a primary GIST resection. We describe an 80-year-old male patient with liver metastasis from a GIST resected 12 years ago. He was admitted for examination of the liver tumor, having previously had a partial gastrectomy for a gastric submucosal tumor. Abdominal enhanced CT revealed an irregular, heterogenous tumor, 75 mm in diameter, in the right lobe.<br> Contrast-enhanced ultrasonography using Sonazoid indicated irregular hyper-enhancement in the vascular phase and hypoecho in the Kupffer phase. We diagnosed a metastatic liver tumor or cholangiocellular carcinoma and performed a right hepatectomy. Microscopic examination revealed that the tumor consisted of uniform and spindle cells with a fascicular growth pattern. Immunohistochemically, c-kit and CD34 were expressed. The tumor was diagnosed as a metastasis of the GIST, the gastric submucosal tumor resected 12 years ago.<br>

Journal

  • Kanzo

    Kanzo 53 (4), 225-230, 2012

    The Japan Society of Hepatology

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