A case of hepatic epithelioid hemangioendothelioma resulting in hepatic failure from tumor dissemination and spread

  • Sunose Yutaka
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Hirai Keitaro
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Yoshinari Daisuke
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Totsuka Osamu
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Toya Hiroyuki
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Ogawa Hiroomi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Takahashi Norifumi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Tanaka Kazumi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Oyama Tetsuya
    Department of Tumor Pathology, Gunma University Graduate School of Medicine
  • Takeyoshi Izumi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine

Bibliographic Information

Other Title
  • 切除不能と診断後,肝不全に至るまでの自然経過を観察し得た肝原発類上皮血管内皮腫の1例
  • 症例報告 切除不能と診断後,肝不全に至るまでの自然経過を観察し得た肝原発類上皮血管内皮腫の1例
  • ショウレイ ホウコク セツジョ フノウ ト シンダン ゴ カンフゼン ニ イタル マデ ノ シゼン ケイカ オ カンサツ シエタ カン ゲンパツルイ ジョウヒ ケッカン ナイヒ シュ ノ 1レイ

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Abstract

A 27-year-old woman was referred to our hospital to investigate liver tumor. The laboratory tests revealed no abnormal finding in blood chemistry. Abdominal CT demonstrated irregular tumor located in the surface of the bilateral hepatic lobe. PET-CT demonstrated no abnormal FDG-accumulation. Histological findings from tumor biopsy showed epithelioid shaped tumor cells with immunohistochemically positive for factor VIII-related antigen, CD31, CD34, and vimentin, and negative for cytokeratin and desmin. The tumor was diagnosed as epithelioid hemangioendothelioma. The patient received transarterial infusion chemotherapy, since curative resection was not possible. The patient did well with no symptom up to 2007. The liver function was deteriorated with tumor extension after 2008. The tumor occupied in the most lesion of the liver, and the patient was suffered with edema and ascites in 2009. On September 2009, her general condition was remarkably worsened, and she died of hepatic failure and peritoneal dissemination of the tumor.<br>

Journal

  • Kanzo

    Kanzo 51 (12), 751-757, 2010

    The Japan Society of Hepatology

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