A case report of hepatocellular carcinoma with bone metastasis successfully treated with assertive combination therapy
-
- Nakahara Hideki
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Itamoto Toshiyuki
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Kohashi Toshihiko
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Omori Ichiro
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Yanagawa Senichiro
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Tanaka Asuka
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Miguchi Masashi
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Akimoto Etsushi
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Egi Hiroyuki
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Kadoya Takayuki
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Matsugu Yasuhiro
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Urushihara Takashi
- Department of Surgery, Hiroshima Prefectural Hospital
-
- Murakami Tomonori
- Department of Radiology, Hiroshima Prefectural Hospital
-
- Kitamoto Mikiya
- Department of Gastroenterology, Hiroshima Prefectural Hospital
Bibliographic Information
- Other Title
-
- 集学的治療によりＣＲを得た肝細胞癌骨転移の１例
- 症例報告 集学的治療によりCRを得た肝細胞癌骨転移の1例
- ショウレイ ホウコク シュウガクテキ チリョウ ニ ヨリ CR オ エタ カン サイボウガンコツ テンイ ノ 1レイ
Search this article
Abstract
A 65-year-old man who had been followed up after diagnosis of hepatitis B visited a hospital because of fever elevation. He was introduced to our hospital and was admitted to our department suffering from hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). Tumor markers were elevated (α-fetoprotein (AFP), 142 ng/ml; des-γ-carboxy prothrombin (DCP), 32038 AU/l), and computed tomography (CT) revealed a large tumor occupying the right lobe of the liver with PVTT occupying the right portal vein to the neck of the left portal vein. Operative diagnosis was HCC (H2, MT-PA multiple, infiltrative type, Ig, FC (-), Fc-inf (-), Sf (-), S0, Vp4, Vv0, Va0, B0, P0) T4N0M0 Stage IVA, and extended right hepatectomy and thrombectomy were performed.<br> He complained of left lumbar pain after the operation and was followed up at the orthopedic department, but his lumbar pain persisted and tumor marker elevation continued. Whole body CT revealed only a large left iliac tumor without liver or lung metastasis. The iliac tumor was treated by radiation therapy with transarterial 5-FU infusion and transarterial chemoembolization.<br> Tumor markers normalized soon after treatment, and 17 months after completion of treatment, CT revealed regeneration of the ilium without bone tumor and no liver or lung metastasis.<br> There is no established treatment for extrahepatic metastasis of HCC, and treatment is limited to radiation for pain control in many patients with bone metastasis. In HCC patients with well-controlled liver condition, assertive combination therapy for distant metastasis is expected to improve the prognosis.<br>
Journal
-
- Kanzo
-
Kanzo 51 (4), 189-195, 2010
The Japan Society of Hepatology
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679771059200
-
- NII Article ID
- 10026393498
-
- NII Book ID
- AN00047770
-
- ISSN
- 18813593
- 04514203
-
- NDL BIB ID
- 10656879
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed
