肝疾患の血清補体に関する研究

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タイトル別名
  • Studies on complement of sera with liver diseases
  • カン シッカン ノ ケッセイ ホタイ ニカンスルケンキュウ トクニ ホタイ タ
  • 特に補体蛋白成分,血清血漿補体価解離現象について

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In measuring serum complement level of patients with liver diseases, higher levels than normal were observed in acute hepatitis, in which the levels decreased in a few week after onset. On the other hand, lower levels of complement were observed in both chronic hepatitis and liver cirrhosis, in which change of complement level was less. <BR>Complement components of C3 and C4 decreased in progress of the disease and these amoumts correlated with total complement levels. <BR>High levels of Clq were observed in liver cirrhosis and its amounts did not correlated with degree of liver damage. <BR>There was no correlation between serum immunoglobulin levels and serum complement levels observed. <BR>A phenomenon of dissociation of complement level between serum and plasma was observed in 7 cases of liver cirrhosis, 6 cases of chronic hepatitis and one case of acute hepatitis. <BR>Complement levels of these 14 cases were lower than that of other cases without dissociation. Among them, 5 cases showed the dissociation all through the period observed, whereas other 9 cases showed wide range of change in complement level and showed no dissociation at their higher levels of complement. <BR>No paticular histological findings nor disfunction except some abnormalities in serological findings were observed.

収録刊行物

  • 肝臓

    肝臓 18 (12), 925-935, 1977

    一般社団法人　日本肝臓学会

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