伝染性単核症肝炎の臨床的研究

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書誌事項

タイトル別名
  • Clinical study on infectious mononucleosis hepatitis
  • デンセンセイ タンカクショウ カンエン ノ リンショウテキ ケンキュウ

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説明

Seven patients with infectious mononucleosis admitted to National Shimonoseki Hospital during recent one year are reported. All cases had characteristic signs and symptoms of infectious mononucleosis as described by Evans, and were complicated by severe hepatitis. The diagnosis was comfirmed by the tests for various antibodies against Epstein-Barr virus. Five of seven patients had significantly high titer of IgM and or IgG antibodies to viral capsid antigen.<BR>Patients with EBV antibody positive infectious mononucleosis tended to have a high levels of serum IgM and patients with EBV antibody negative infectious mononucleosis tended to show high level of serum transaminase.<BR>In infectious mononucleosis hepatitis of all 4 cases studied, focal necrosis was observed as Well as portal and intralobular infiltlates of inflammatory cells, predominantly lymphocytes. The present study indicates that infectious mononucleosis is not so rare in Japan and sometimes complicates with severe hepatitis.

収録刊行物

  • 肝臓

    肝臓 21 (11), 1513-1519, 1980

    一般社団法人　日本肝臓学会

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