The effect of a multiple drug therapy with Inchinkoto, a herbal medicine on bile acids and bilirubin in two patients with prolonged severe mixed type of drug induced liver injury
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- Sakemi Ryosuke
- Department of Gastroenterology, Tobata Kyoritsu Hospital
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- Kakiuchi Seiya
- Department of Gastroenterology, Tobata Kyoritsu Hospital
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- Morimitsu Yosuke
- Division of Pathology, Tobata Kyoritsu Hospital
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- Kubo Yasuhiko
- Division of Pathology, Tobata Kyoritsu Hospital
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- Matsugaki Satoru
- Division of Pathology, Tobata Kyoritsu Hospital
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- So Suketo
- Division of Pathology, Tobata Kyoritsu Hospital
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- Sakemi Miyuki
- Division of Pathology, Tobata Kyoritsu Hospital
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- Shimokobe Masayuki
- Department of Gastroenterology, Tobata Kyoritsu Hospital
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- Harada Masaru
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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- Sata Michio
- Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine
Bibliographic Information
- Other Title
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- 遷延した混合型薬物性肝障害に対して茵陳蒿湯を含む多剤薬物療法が有効であった2例
- 症例報告 遷延した混合型薬物性肝障害に対して茵陳蒿湯を含む多剤薬物療法が有効であった2例
- ショウレイ ホウコク センエン シタ コンゴウガタ ヤクブツセイ カン ショウガイ ニ タイシテ インチンコウトウ オ フクム タザイ ヤクブツ リョウホウ ガ ユウコウ デ アッタ 2レイ
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Abstract
Two adult males were admitted to our hospital because of the liver dysfunction with jaundice. Both patients had received tranilast to prevent keloid formation after the external injury. Liver biopsy revealed cholestatic liver injury in both cased. Drug-induced lymphocyte stimulation test for tranilast was negative in both cases. However, based on the absence of other causes of liver dysfunction, drug-induced liver injury was suspected. Ursodeoxycholic acid was administered, but it was not effective in both cases. We introduced Inchinkoto resulting in a remarkable improvement of liver dysfunction. Inchinkoto must be one of the therapeutic options for cholestatic liver injury.<br>
Journal
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- Kanzo
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Kanzo 53 (5), 291-297, 2012
The Japan Society of Hepatology
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Keywords
Details 詳細情報について
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- CRID
- 1390282679771469952
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- NII Article ID
- 10030625556
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 023658491
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed