A case of biopsy-proven idiopathic peliosis hepatis disseminated to whole liver with rapidly worsening course

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  • Kitahara Takuya
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Kubo Yasuhito
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Yoshizawa Kai
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Abe Hiroshi
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Aizawa Ryouichi
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Masuoka Mika
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Aizawa Yoshio
    Department of Gastroenterology and Hepatology, Aoto Hospital of the Jikei University School of Medicine
  • Sunagawa Keishin
    Department of Pathology, Nihon University School of Medicine
  • Takayama Tadatoshi
    Devision of Digestive Surgery Nihon University Scool of Medicine
  • Makuuchi Masatoshi
    Japanese Red Cross Medical Center

Bibliographic Information

Other Title
  • 進行性で致命的な経過をたどった特発性Ｐｅｌｉｏｓｉｓ　ｈｅｐａｔｉｓの１例
  • 症例報告 進行性で致命的な経過をたどった特発性Peliosis hepatisの1例
  • ショウレイ ホウコク シンコウセイ デ チメイテキ ナ ケイカ オ タドッタ トクハツセイ Peliosis hepatis ノ 1レイ

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Description

Here we report a 62 y/o male who was diagnosed as idiopathic peliosis hepatis by liver biopsy and had a rapidly worsening course complicated with disseminated intravascular coagulation (DIC). He was pointed out liver dysfunction by routine check-up, and diagnosed as having peliosis hepatis that was distributed to whole liver by liver biopsy and abdominal CT at the beginning of September 2006. He was followed-up regularly afterward. He has been symptom-free with mild unchanged liver dysfunction until the middle of August 2007, when he suddenly complained back pain and right hypochondralgia with remarkable hepatomegaly. The blood tests showed that he had DIC with remarkable worsening of liver function. Living donor liver transplantation was planned. However, he developed hepatic failure complicated with pneumonia to die 2 months later with no chance for the liver transplantation. The present case suggests that peliosis hepatis disseminated to whole liver might cause DIC thus needs careful follow up.<br>

Journal

  • Kanzo

    Kanzo 50 (5), 229-237, 2009

    The Japan Society of Hepatology

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