Two cases of acute hepatitis due to hepatitis E virus that are indigenous to Kitakyushu: a case report

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  • Honma Yuichi
    Department of Gastroenterology and Hepatology, Sangyoikadaigaku Wakamatsu Hospital Third Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine
  • Tabaru Akinari
    Department of Gastroenterology and Hepatology, Sangyoikadaigaku Wakamatsu Hospital
  • Kita Eisaku
    Department of Gastroenterology and Hepatology, Sangyoikadaigaku Wakamatsu Hospital
  • Matsuoka Hidehiko
    Department of Gastroenterology and Hepatology, Sangyoikadaigaku Wakamatsu Hospital
  • Shukuwa Kazutaka
    Department of Gastroenterology and Hepatology, Sangyoikadaigaku Wakamatsu Hospital
  • Takahashi Kazuaki
    Department of Medical Sciences, Toshiba General Hospital
  • Arai Masahiro
    Department of Medical Sciences, Toshiba General Hospital
  • Harada Masaru
    Third Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine

Bibliographic Information

Other Title
  • 北九州に土着したE型肝炎ウイルス株による急性肝炎の2例
  • B型肝炎治療ガイドライン(第1.1版)
  • Bガタ カンエン チリョウ ガイドライン(ダイ1.1ハン)
  • キタキュウシュウ ニ ドチャク シタ Eガタ カンエンウイルスカブ ニ ヨル キュウセイ カンエン ノ 2レイ
  • Guidelines for the management of hepatitis B virus infection

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Description

Two male patients with liver dysfunction were admitted to our hospital and diagnosed to acute hepatitis E by detection of IgA class anti-Hepatitis E virus antibody and Hepatitis E virus (HEV) RNA. Following admission, liver dyfunction was improved by conservative treatment. Although the infection route of HEV was unknown, analysis of HEV genome sequence revealed that the HEV isolated from the two cases belonged to genotype 3 and had homology. So we considered that the HEV strains were presumed to be indigenous to Kitakyushu. Because fulminant hepatitis due to HEV has been reported, even in nonepidemic area, we need to pay attention to acute hepatitis E in treatment of patients with liver dysfunction of unknown origin.<br>

Journal

  • Kanzo

    Kanzo 54 (6), 399-401, 2013

    The Japan Society of Hepatology

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