Two cases of acute hepatitis type C that improved with multidisciplinary therapy and interferon

  • Iwashita Hideyuki
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Shakado Satoshi
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Nishizawa Shinya
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine Department of Emergency and Critical Care Medicine, Fukuoka University
  • Kuno Shizuka
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine Department of Emergency and Critical Care Medicine, Fukuoka University
  • Matsumoto Teruo
    Department of Hepatology, Hakujyuji Hospital
  • Kunimoto Hideo
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Yotsumoto Kaoru
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Fukunaga Atsushi
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Sakurai Kunitoshi
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Hirano Genryu
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Ueda Syuichi
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Yokoyama Keiji
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Morihara Daisuke
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Sakamoto Masaharu
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Anan Akira
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Takeyama Yasuaki
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Irie Makoto
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Iwata Kaoru
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Ohta Kazuhiro
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Sohda Tetsuro
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine
  • Inoue Kazuaki
    Department of Gastroenterology and Medicine, Showa University Fujigaoka Hospital
  • Yoshiba Shinsyo
    Department of Gastroenterology and Medicine, Showa University Fujigaoka Hospital
  • Sakisaka Shotaro
    Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine

Bibliographic Information

Other Title
  • インターフェロン併用集学的治療を行ったC型急性肝炎の2例
  • 症例報告 インターフェロン併用集学的治療を行ったC型急性肝炎の2例
  • ショウレイ ホウコク インターフェロン ヘイヨウシュウガクテキ チリョウ オ オコナッタ Cガタ キュウセイ カンエン ノ 2レイ

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Abstract

The first case was a male in his 30's who was taking an antiepileptic agent for the treatment of lifelong epilepsy. He was being treated at a local clinic but developed severe liver dysfunction and lowered consciousness. Prothrombin time activity was less than 40% with grade II hepatic encephalopathy. He was diagnosed with acute liver failure due to hepatitis C virus (HCV). The route of infection was uncertain. The second case was a male in his 30's. He had been infected with HCV tainted blood and developed acute hepatitis type C (AHC). After admission, low prothrombin activity continued, and icterus was prolonged. Both cases were done with immediate multidisciplinary therapy including interferon (IFN), leading to significant improvement. After overcoming the acute stage IFN was continued for 24 weeks and persistent HCV infection was prevented in both cases. It was suggested that IFN was a useful treatment for acute liver failure due to HCV or AHC.<br>

Journal

  • Kanzo

    Kanzo 53 (2), 101-108, 2012

    The Japan Society of Hepatology

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