ある施設に集団発生したA型肝炎について

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タイトル別名
  • Studies on an out break of hepatitis A in an institute for the mentally retarted children
  • アル シセツ ニ シュウダン ハッセイシタ Aガタ カンエン ニ ツイテ

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抄録

The authors encountered an outbreak of acute hepatitis in an institute for the mentally retarted children in Aomori Prefecture.<BR>From the clinical and epidemiological investigations of affected 41 children and staffs, it was suggested to be typical out break of hepatitis A. Immune electron microscopy disclosed hepatitis A virus particles in stool specimens of four patients, which were collected in a few days before and after onset of symptoms. The antigen was further extracted and purified by ultracentrifugation.<BR>Subsequently, in the immune adherence hemagglutination test using this extracted antigen, a significant increased hepatitis A antibody of the paired sera was revealed. Thus, diagnosis of hepatitis A was confirmed serologically.<BR>Human immune serum globulin for protection against hepatitis was administered to the 80 individuals concerned, and was effective to prevent the manifestation of hepatitis A.

収録刊行物

  • 肝臓

    肝臓 19 (1), 9-21, 1978

    一般社団法人　日本肝臓学会

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