A case report of hepatocellular carcinoma adjacent to hepatic biloma successfully treated by stereotactic body radiation therapy

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  • Makino Yuki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Sakamori Ryotaro
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Shiomi Hiroya
    Department of Radiology, Saito-Yukokai Hospital
  • Yakushijin Takayuki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Hikita Hayato
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Oze Tsugiko
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Yosida Yuichi
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Tatsumi Tomohide
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Hiramatsu Naoki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Nakamura Hironobu
    Department of Radiology, Saito-Yukokai Hospital
  • Takehara Tetsuo
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine

Bibliographic Information

Other Title
  • bilomaに隣接した肝細胞癌に対して定位放射線療法が奏功した一例
  • 症例報告 bilomaに隣接した肝細胞癌に対して定位放射線療法が奏功した一例
  • ショウレイ ホウコク biloma ニ リンセツ シタ カン サイボウ ガン ニ タイシテ テイイ ホウシャセン リョウホウ ガ ソウコウ シタ イチレイ

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Abstract

A 80-year-old man had been regularly followed up for hepatitis C since 2002. After hepatocellular carcinoma (HCC) initially developed in 2007, he underwent radiofrequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) for several times. In 2013, 15-mm HCCs recurred both in segments 3 and 5. We first conducted TACE and percutaneous ethanol injection therapy was added for HCC in segment 3. However, since HCC in segment 5 was adjacent to biloma developed by the past RFA, we performed stereotactic body radiation therapy (SBRT) with a total dose of 40 Gy in 4 fractions. Consequently, complete response was achieved one month after SBRT without any adverse events. This lesion has been recurrence-free for 22 months. This is the first case report of HCC adjacent to biloma successfully treated by SBRT. Whereas ablation therapies have a risk of bile duct injury, SBRT might be a safe and effective treatment option.

Journal

  • Kanzo

    Kanzo 57 (1), 17-26, 2016

    The Japan Society of Hepatology

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