慢性肝疾患時の耐糖能異常に関する臨床的検討

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書誌事項

タイトル別名
  • The Relationship Between Glucose Tolerance and Pancreatic
  • マンセイ カン シッカンジ ノ タイトウノウ イジョウ ニ カンスル リンショ
  • Exocrine or Endocrine Function in Chronic Liver Diseases
  • とくに膵障害の関与について

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抄録

Pancreozymin-secretin test and glucose tolerance test were performed in 101 patients with chronic liver diseases. Responses of serum insulin and plasma glucagon to glucose or arginine load were also studied in some cases of them.<BR>Mild pancreatic exocrine insufficiency was found in 35% of all subjects, but these cases showed no different glucose tolerance and pancreatic endocrine function from those which healthy controls did. Moderate to severe insufficiency was observed in 11% of non-cirrhotic cases and in 6% of cirrhotic cases, and most of them were alcoholics. In these cases glucose intolerance or pancreatic endocrine insufficiency were more often found than mild exocrine insufficient cases.<BR>These results suggest that pancreatic disorder dose not influence on glucose tolerance in all cases with chronic liver diseases, but in non-cirrhotic alcoholics it has important roles. So, in such cases pancreatic exocrine and endocrine function must be studied to determine whether concomitant pancreatic disorder results in glucose intolerance.

収録刊行物

  • 肝臓

    肝臓 19 (3), 270-278, 1978

    一般社団法人　日本肝臓学会

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