A Case of Prepubertal Unilateral Fibrous Hyperplasia of the Labium Majus

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  • Yabe Kiyoaki
    Department of Pediatric Surgery, Tokyo Women’s Medical University Yachiyo Medical Center
  • Matsuoka Aki
    Department of Pediatric Surgery, Tokyo Women’s Medical University Yachiyo Medical Center
  • Takenouchi Ayako
    Department of Pediatric Surgery, Tokyo Women’s Medical University Yachiyo Medical Center
  • Kouchi Katsunori
    Department of Pediatric Surgery, Tokyo Women’s Medical University Yachiyo Medical Center

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Other Title
  • 思春期前の女児に生じた片側大陰唇の腫大prepubertal unilateral fibrous hyperplasia of the labium majusの1例
  • 症例報告 思春期前の女児に生じた片側大陰唇の腫大prepubertal unilateral fibrous hyperplasia of the labium majusの1例
  • ショウレイ ホウコク シシュンキ マエ ノ ジョジ ニ ショウジタ カタガワダイイン シン ノ シュダイ prepubertal unilateral fibrous hyperplasia of the labium majus ノ 1レイ

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Abstract

Prepubertal unilateral fibrous hyperplasia (PUFH) of the labium majus is characterized by unilateral soft tissue enlargement of the labium majus in prepubertal girls. An 8-year-old girl presented with a painless swelling of the left labium majus. The left labium majus showed a soft and ill-defined enlargement. T1- and T2-weighted MR images revealed a hypointense and ill-defined mass in the left labium majus. Enhanced contrast CT showed a hypovascular mass. These imaging examinations suggested the growth of fibrous tissue in the labium majus. The lesion enlarged gradually. We extirpated the mass. Histopathologic findings revealed PUFH. The patient has been followed up for two years without recurrence. PUFH is a new disease and the literature on this condition is scant, but we take into consideration PUFH as a differential diagnosis of the unilateral swelling of the labium majus in prepubertal girls.

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