Evaluation of the Effects of Tretinoin Tocoferil Ointment (Olcenon Ointment) in the Treatment of Decubitus and Skin Ulcers.

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Other Title
  • トレチノイン　トコフェリル含有軟膏（オルセノン軟膏）のじょくそう・皮膚潰ように対する臨床試験成績

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Description

In order to investigate the usefulness of tretinoin tocoferil ointment, a multicenter collaborative open clinical study was conducted subjecting 32 patients suffering from decubitus, leg ulcer, diabetic ulcer and other intractable ulcers. The age of the patients ranged 21-96 years and mean age was 63.0 years. The application of this ointment was once or twise daily. Results obtained were following; marked improvement in 17 (53%), moderate improvement in 5 (16%), slight improvement in 5 (16%). Especially, the drug was excellently effective on granulation and epithelization. A clinical adverse reactions were seen in 4 of 32 (irritation, rash around ulcer and so on). Thus, final utility ratio was 72% (23/32).<BR>The results of our study support the efficacy and safety of tretinoin tocoferil ointment in the management of decubitus and skin ulcers.

Journal

  • Skin research

    Skin research 36 (2), 209-219, 1994

    Meeting of Osaka Dermatological Association

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Details 詳細情報について

  • CRID
    1390282679776437504
  • NII Article ID
    130004045592
  • DOI
    10.11340/skinresearch1959.36.209
  • ISSN
    1884541X
    00181390
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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