Serum Androgen Levels in Women with Acne Vulgaris: The Effect of Shakuyaku-Kanzo-To(SK).

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Bibliographic Information

Other Title
  • 女性ざそう患者の血中ホルモン動態：しゃく薬甘草湯投与の影響

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Description

In order to evaluate the role of androgens in the pathogenesis of acne, the efficacy of Shakuyaku-Kanzo-To (SK) in the treatment of acne was evaluated in 29 women with acne. SK (7. 5 g /day) were administered daily for 12 weeks to 29 acne patients. Serum levels of testosterone (T), free testosterone (FT), dihydrotestosterone (DHT), dehydoepiandrosterone sulfate (DHEA -S) and sex hormone binding globulin (SHBG) were measured by RIA during the mid follicular phase. While taking SK, serum FT levels were significantly lower than those in the basal levels. The other hormone levels showed no significantly differences between the basal and the treatment levels. SK was significantly effective in reducing the numbers of comedones. 18 of the 29 patients had a good response. These results suggest that SK is effective in the treatment of acne vulgaris in accordance with reducing the serum FT levels.

Journal

  • Skin research

    Skin research 38 (1), 37-41, 1996

    Meeting of Osaka Dermatological Association

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Details 詳細情報について

  • CRID
    1390282679776457088
  • NII Article ID
    130004045702
  • DOI
    10.11340/skinresearch1959.38.37
  • ISSN
    1884541X
    00181390
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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