Clinical evaluation of hair regrowth tonics containing oleanolic acid.

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  • オレアノール酸配合育毛剤の臨床試験結果

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To evaluate the hair regrowth effect of oleanolic acid, a well controlled half side test was conducted at apparently normal sites in 14 males with alopecia praematura.<BR>The hair regrowth tonic formulated with 22.5% swertia extract containing oleanolic acid and swertiamarin was supplied by the Institute of Applied Biochemistry.<BR>In the active sites, the number of hairs in the area of 1 cm circle on the scalp were significantly increased after 4 months administration of this tonic. In placebo sites, however, the number of hairs were not significantly increased. The clinical effects were marked in 3 patients. No severe side effect was seen except for itching in 1 patient. We confirmed this hair regrowth tonic was effective and safe for the treatment of alopecia praematura.

Journal

  • Skin research

    Skin research 31 (4), 541-547, 1989

    Meeting of Osaka Dermatological Association

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