Pitted Keratolysis.

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  • Ｐｉｔｔｅｄ　Ｋｅｒａｔｏｌｙｓｉｓ

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Six cases of pitted keratolysis were reported and reviewed the reported cases of pitted keratolysis in Japan. Our three patients were female. All six patients complained of malodor and hyperhidrosis. They developed pitted erosions of the stratum corneum on the soles of the feet. Five patients had sore foot in walkig.Corynebacterium sp. and micrococcus sp. were isolated from the lesions of three patients. All six patients were treated with josamycin. Within a few weeks, the symptoms and the eruption were subsiding. The biopsy specimens showed that the pits were confined completely to the stratum corneum. The organism was at the base and sides of the pit. Coccoid bodies are frequently seen near the surface of stratum corneum and filamentous organisms are seen infiltrating the stratum corneum. Several organisms have been implicated as the etiological agent of pitted keratolysis. On the basis of microscopic findings and the cultural findings, both of micrococcus sp. and corynebacterium sp. may be etiological agents in most cases of pitted keratolysis. The other organisms also may be etiological agent in a few cases.

Journal

  • Skin research

    Skin research 36 (5), 655-662, 1994

    Meeting of Osaka Dermatological Association

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