Two Cases of Occult Breast Cancer Presenting as Metastatic Axillary Tumor

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  • 腋窩リンパ節転移で発見され胸筋温存乳房切除術を施行した潜在性乳癌の２例
  • エキカ リンパセツ テンイ デ ハッケン サレ キョウキン オンゾン ニュウボウ セツジョジュツ オ セコウ シタ センザイセイ ニュウガン ノ 2レイ
  • 症例報告 腋窩リンパ節転移で発見され胸筋温存乳房切除術を施行した潜在性乳癌の2例
  • ショウレイ ホウコク エキカリンパセツ テンイ デ ハッケン サレ キョウキン オンゾン チブサ セツジョジュツ オ シコウ シタ センザイセイ ニュウガン ノ 2レイ

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Abstract

<p>Case 1：A 72-year-old woman visited us with a complaint of right axillary lymph node swelling. Breast cancer metastases to the axillary lymph nodes were suspected. Even with mammography（MMG），ultrasound（US），computed tomography（CT），and magnetic resonance imaging（MRI），the primary lesion could not be identified. Axillary lymph node biopsy revealed invasive lobular breast carcinoma. She was diagnosed with latent breast cancer and underwent mastectomy and axillary lymphadenectomy. Case 2：A 60-year-old woman visited us with a complaint of right axillary lymph node swelling. Despite various examinations, including MMG, US, CT and MRI as in Case 1, the primary lesion could not be identified. Axillary lymph node biopsy revealed invasive ductal breast carcinoma, leading to a diagnosis of latent breast cancer. She underwent mastectomy and axillary lymphadenectomy. Postoperatively, both patients have remained recurrence-free for two years to date. Latent breast cancer develops at a low incidence, 0.3－1% of all breast cancers, and therapeutic strategies are determined on an individual basis at each institution. While insufficient treatment increases the possibility of recurrence and metastasis, excessive therapy should be avoided. Therefore, determining the optimal therapeutic strategy can be challenging. We advocate accumulating more cases to establish systematic therapeutic guidelines.</p>

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