X-RAY IRRADIATION FOR THE PREVENTION OF KELOID AFTER CLEFT LIP PLASTY

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  • 口唇裂術後のケロイド予防におけるX線照射

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Abstract

To determine the usefulness and problems of X-ray irradiation used for the prevention of keloid, we reviewed 164 patients followed up over 6 months after cleft lip plasty. X-ray irradiation, in total doses of 600 R or 900 R in 3 fractions, usually started within 5 days after the plasty, and was completed befor the surgical threads were removed. A tube voltage of 30 KV or 45 KV was determined by the depth of the suture site. The incidence of keloid after irradiation was significantly lower than without irradiation. X-ray irradiaten was confirmed to be useful for preventing keloid after cleft lip plasty. Our conditions with respect to the starting time of X-ray irradiation, period, or number of fractions were considered to have no specific disadvantages over other conditions. There was no significant difference, in terms of incidence of keloid, between total doses 600 R and 900 R, although cases, in which keloid was more likely to occur, were irradiated with 900 R, The most important reason for the insignificant difference in the incidence of keloid after 600 R and 900 R was thought to be the small total dose. There was no significant difference between 30 KV and 45 KV in the incidence of keloid. This indicates that there might be no special advantage to X-ray irradiation with 45 KV. It is speculated that the incidence of keloid might be reduced more by increasing the total dose to 1200-1500 R. Although increasing the total dose this much will probably not cause increased pigmentation, further study of several cases is necessary.

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