IMMUNOCYTOCHEMICAL STUDIES OF GLUTAMATE-LIKE IMMUNOREACTIVE NEURONS IN THE RAT HYPOTHALAMUS
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- HORI Yasunori
- Department of Anatomy, Showa University School of Medicine
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- SUKAGAWA Keiko
- Department of Anatomy, Showa University School of Medicine
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- OCHIAI Hidehiko
- Department of Anatomy, Showa University School of Medicine
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- NAKAI Yasumitsu
- Department of Anatomy, Showa University School of Medicine
Bibliographic Information
- Other Title
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- ラット視床下部におけるグルタミン酸含有ニューロンの免疫電顕的観察
- —Synaptic Interactions between Glutamate and Somatostatin Neurons—
- ―ソマトスタチン含有ニューロンとの形態学的相関について―
Abstract
Ultrastructure of glutamate-like immunoreactive (Glu-LI) neurons in the rat hypoth-alamus was studied immunocytochemically using Glu antibody. Synaptic Interactions between Glu-LI neurons and somatostatin-like immunoreactive (SRIF-LI) neurons were examined ultrastru-cturally by a pre-embedding double immunostaining technique combining the silver-gold intensified peroxidase-antiperoxidase complex-3, 3'-diaminobenzidine (SGI-PAP-DAB) method with the nonintensified ABC-DAB method. Glu-LI axon terminals were found directly terminating on the basal lamina of the blood capillaries of the portal vessels in the median eminence. Glu-LI neurons received synaptic inputs from unknown neurons in the arcuate nucleus. Synaptic interactions between Glu-LI and SRIF-LI neurons were found in the periventricular nucleus. In the arcuate nucleus, synapses occurred between Glu-LI axons and dendrites. These findings suggest that Glu-LI neurons may regulate the secretory activity of growth hormone-producing cells directly or indirectly through synapses with SRIF-LI neurons.
Journal
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- Journal of The Showa Medical Association
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Journal of The Showa Medical Association 57 (1), 56-63, 1997
The Showa University Society
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Details 詳細情報について
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- CRID
- 1390282679811134336
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- NII Article ID
- 130001824659
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- ISSN
- 21850976
- 00374342
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed