HISTOPATHOLOGICAL AND HISTOMORPHOMETRICAL STUDY OF AVASCULAR NECROSIS OF FEMORAL HEADS
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- HARA Hiroaki
- The Second Department of Pathology, School of Medicine, Showa University Department of Oral Pathology, School of Dentistry, Showa University
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- TSUCHIYA Tsuneatsu
- Department of Orthopaedic Surgery, Kawasaki Kyodo Hospital
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- HORIUCHI Shizuo
- Department of Orthopaedic Surgery, Kawasaki Kyodo Hospital
Bibliographic Information
- Other Title
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- 特発性大腿骨頭壊死の病理組織学的ならびに骨形態計測学的研究
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Abstract
Histological study of avascular necrosis of femoral heads were conducted in 20 hips by histomorphometric methods. Especially, the femoral head repairing process was studied by contact microradiogram and tetracycline double labelling. Beneath the cartilage layer, four different layers, the necrotic zone, the fibrous band, the sclerosing zone, and the normal cancellous zone were found in femoral head specimens. Thick appositional woven bone with osteoid matrix and active osteoblasts wos prominent in the sclerosing zone. Primary, secondary, and dynamic parameters of the trabecular bone were measured in the sclerosing zone and the normal cancellous zone of the femoral heads. The trabecular bone specific volume (tVsp) of the sclerosing zone was about four times that of the normal cancellous zone. Both the fractional formation surface (FrFS) and the fractional resorption surface (FrRS) of the sclerosing zone were about three times those of the normal cancellous zone. When observed by tetracycline double labelling, the tetracycline labelled surface of the sclerosing zone was three times that of the normal cancellous zone. The mineral appositional rate (Mo) was about 2.2 μm/day in the sclerosing zone and about 1.4μm/day in the normal cancellous zone. Thus, good repairing capacity was observed quantitatively in the specimens of avascular necrosis of femoral heads.
Journal
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- Journal of The Showa Medical Association
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Journal of The Showa Medical Association 48 (5), 607-616, 1988
The Showa University Society
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Details 詳細情報について
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- CRID
- 1390282679811495552
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- NII Article ID
- 130001828293
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- ISSN
- 21850976
- 00374342
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed