ナフタリン中毒症に於ける心臓の変化に就て

大森 進

doi:10.14930/jsma1939.20.1335

1. Normal pure bred rabbits were employed in the present experiment. They were divided into 4 groups of Group I intraperitoneal infusion of naphthaline-olive-oil, Group II vitamin C injection in combination with the intragastric infusion of olive oil, Group III administration of naphthaline powder mixed in vitamin C deficient diet (a) and normal diet (b) and Group IV subcutaneous injection of naphthalene -olive-oil. Then, histopathological studies were made on the heart of those rabbits.<BR>2. Of the groups under long period observation, the myocardiac fibers of the rabbits in Group E showed fairly strong vacuolar degeneration and minute separation of the fiber as well as mild granular degeneration, swelling colliquative change, homogenization, atrophy, crumbling, irregular arrangement, hyaline degeneration etc. Those changes were slightly stronger than the changes observed on the group of vitamin C deficient diet.<BR>3. Absorption of naphthalene administered by subcutaneous injection was poor in comparison with that of the oral administration and intraperitoneal infusion. This poor absorption is also indicated in the fact that the changes produced in the tissues by the changes produced in the tissues by the subcutaneous injection of naphthalene from the maximun dose of 30% (1g/kg) to the minimum of 10% (0.1g/kg) were extremely weak without too much difference.

ナフタリン中毒症に於ける心臓の変化に就て

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ナフタリン中毒症に於ける心臓の変化に就て

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収録刊行物

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