A Case of Early Gastric Cancer that Developed 6 Years after Eradication of Helicobacter pylori for Nodular Gastritis

  • YASUDA Mayumi
    Gastroenterology and Hepatology(Internal Medicine Ⅰ.),Yamaguchi University Graduate School of Medicine
  • OKAMOTO Takeshi
    Gastroenterology and Hepatology(Internal Medicine Ⅰ.),Yamaguchi University Graduate School of Medicine
  • NAGAO Misato
    Gastroenterology and Hepatology(Internal Medicine Ⅰ.),Yamaguchi University Graduate School of Medicine
  • SASAKI Sho
    Gastroenterology and Hepatology(Internal Medicine Ⅰ.),Yamaguchi University Graduate School of Medicine

Bibliographic Information

Other Title
  • 鳥肌胃炎に対するHelicobacter pylori除菌治療の6年後に発見された未分化型早期胃癌の1例
  • トリハダ イエン ニ タイスル Helicobacter pylori ジョキン チリョウ ノ 6ネンゴ ニ ハッケン サレタ ミブンカガタ ソウキ イガン ノ1レイ
  • 症例報告 鳥肌胃炎に対するHelicobacter pylori除菌治療の6年後に発見された未分化型早期胃癌の1例
  • ショウレイ ホウコク トリハダ イエン ニ タイスル Helicobacter pyloriジョキン チリョウ ノ 6ネンゴ ニ ハッケン サレタ ミブンカガタ ソウキ イガン ノ 1レイ

Search this article

Description

The patient was a 34-year-old female who visited our hospital in May 2008 for a chief complaint of nausea and lower abdominal pain upon fasting. Esophagogastroduodenoscopy(EGD)revealed nodular gastritis in the gastric antrum. Blood test showed positive for anti-Helicobacter pylori IgG antibody. We performed eradiation therapy for Helicobacter pylori. After eradiation therapy, urea breath test showed successful eradiation.6 years after the successful eradiation, the patient visited our hospital again due to nausea/vomiting and diarrhea in January 2014. EGD indicated early gastric cancer on the anterior wall of the gastric middle body, and biopsy detected undifferentiated cancer. Distal gastrectomy, D2 dissection, and Billroth-I reconstruction were performed. Histopathological analysis revealed signet ring cell cancer with an invasion depth of SM2 and multiple regional lymph nodes metastases. Atrophy, inflammatory cell infiltrate, and intestinal metaplasia were not detected in the non-cancer mucosa.Nodular gastritis is observed in young patients with Helicobacter pylori infection, and can induce gastric cancer. However, the clinical course after eradication therapy is still unclear. We reported an example of early gastric cancer that developed after a long-term period(6 years)after eradication therapy in this report.

Journal

References(3)*help

See more

Details 詳細情報について

Report a problem

Back to top