THE CHANGES OF CATECHOLAMINE FLUORESCENCE IN THE WALL OF SMALL ARTERIES AND ADRENAL MEDULLA AFTER THE HISTAMIN AND BRADYKININ SHOCK

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  • Nakashita Kiyoshi
    The First Department of Internal Medicine, School of Medicine, Showa University

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Other Title
  • ブラディキニンおよびヒスタミンショックにおける細動脈壁および副腎髄質のカテコールアミンの変動
  • ブラディキニン オヨビ ヒスタミンショック ニ オケル サイドウミャクヘキ オヨビ フクジン ズイシツ ノ カテコールアミン ノ ヘンドウ

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The guinea pigs were provocated by the injection of 0.5 ml of 0.01% histamine solution and 0.5 ml of 0.01% bradykin in solution. I used Carlsson's method to study the changes of fluorescence in adrenal medulla and the wall of small arteries of the lung, heart and intestine. In adrenall medulla, no marked change of fluorescence of cetecholamine was recognized after injecting of histamin and bradykinin solution. In arteriale walls of the lung, the decrease of fluorescent intesity of noradrenaline were detected after the injection. Meanwhile, in the arteriale walls of intestine, the fluorescent intensity of noradrenaline was followed by little change after injection of histamine and bradykinin solution. In this experiment, I recognized that the fluorescent intensity in arteriale walls of the respiratory system was decreased, but in the digestive system, little change was detected in anaphylactic shock. The distribution of noradrenaline fluorescence in the coronary arteries was noticed to be different f roni other arteries.

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