HISTOPATHOLOGICAL STUDIES ON THE HALF FETAL AND NEONATAL THYROID GLANDS

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  • 胎生後半期及び新生児期に於ける甲状腺の病理形態学的研究
  • 胎生後半期及び新生児期に於ける甲状腺の病理形態学的研究--特に分化発育の他臓器との相関性について
  • タイセイ コウハンキ オヨビ シンセイジキ ニ オケル コウジョウセン ノ ビ
  • —ESPECIALLY CORRELATION WITH DIFFERENTIATION AND DEVELOPMENT OF THE OTHER INTERNAL ORGANS—
  • ―特に分化発育の他臓器との相関性について―

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Abstract

Of 279 cases, which have been autopsied at the 1st Department of pathology, Showa University School of Medicine during the past 6 years from 1971 to 1976, 161 still-born or neonatal infants who were born from mother who had a disease that could give rise to so called immature, postmatuated, and malformed infants were excluded from this research and the rest 118 infants classified into AFD, SFD, LFD according to gestational weeks and body weight. The differentiation and development of the thyroid during the late half fetal and neonatal perioid of each case was studied histopathologically. Moreover, the other internal organs were correlated with the thyroid gland during these periods. That is, the differentiation and development were compared histopathologically<BR>The results obtained are as follows ;<BR>1) On SFD, most cases reveal only the first development but some cases reveal the second development in early stage, and in each case differentiation and development between parenchyma and mesenchyma often shows lack of balance.<BR>2) On LFD, the first and the second development were observed at a higher rate than on SFD. And in each case differentiation and development between parenchyma and mesenchyma were in parallel equally on AFD.<BR>3) On neonatal stage, the differentiation and development of the thyroid gland were observed only on the thyroid before completion of the first development, but on the thyroid, either the first development is completed at birth or, the differentiation and development of thyroid gland shows a tendency not to progress.<BR>4) On the late half fetal stage, the differentiation and development of the thyroid gland showed characteristic two phase pattern and differed from that of the other organs, lung, kidney and aderenal gland.<BR>And abnormality and immaturity of the development and differentiation of the thyroid gland on SFD and LFD were extremely remarkable compared with that of the other organs. So the author infers that the fetal thyroid gland develops most variously histopathologically compared with the other organs.

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