Effect of Ceruloplasmin as a Controlling Factor of the Hematopoietic system on DNA Synthesis of Bone Marrow Cells

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  • Nakao Hiroshi
    Department of 2nd Internal Medicine, School of Medicine, Showa University

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  • セルロプラスミンの骨髄DNA合成に及ぼす造血調整因子としての効果
  • セルロプラスミンの骨髄DNA合成に及ぼす造血調整因子としての効果〔英文〕
  • セルロプラスミン ノ コツズイ DNA ゴウセイ ニ オヨボス ゾウケツ チョウセイ インシ ト シテ ノ コウカ エイブン

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Abstract

It has been shown that the effect of ceruloplasmin is a new one of conditions which accelates erythropoietic activity. It is presented data obtained by autoradiographic methods combined with tissue culture to show that erythropoietc activity induced by ceruloplasmin causes an increase of DNA synthesis by marrow cells as well as anemic or hypoxic status. But it is not clear whether this increase in DNA synthesis may associated with an increase in hemoglobin synthesis.

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